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technet21 postspacerThe Role of Developing Country Manufacturers in Providing Innovative Vaccines

technet21 postspacerFamily Planning and Immunization Integration: Information Request

technet21 postspacerTechnical and Commercial Feasibility of Stabilizing Vaccines: PATH Study

technet21 postspacerDisposal of Pre-Filled Glass Syringes?

Issue 52, 3 May 2010

 
Editorial Note

Due to internal contingencies, we had to skip the 25 April 2010 issue. Many apologies to our readers.

In this issue, Julie Milstien summarises an article written by Miloud Kaddar and her titled 'The role of emerging manufacturers in access to innovative vaccines of public health importance', published in Vaccine. Family Health International asks readers to write in with information about programmes integrating family planning with child immunization activities. Faisal Mansoor poses a question about vaccine freezing, and Toryalai Hart shares information about glass crushers for medical waste glass. He also inquires whether readers know of any commercial enterprise that makes use of crushed glass.


by Julie Milstien and Miloud Kaddar

A recently published paper (JB Milstien and M Kaddar. 'The role of emerging manufacturers in access to innovative vaccines of public health importance', Vaccine 28: 2115-2121, 2010) analyzes the potential for emerging suppliers, those vaccine manufacturers located in developing countries, to supply innovative vaccines in the international public market. The current situation was compared to results obtained from a study performed for the GAVI Alliance by the Boston Consulting Group, in collaboration with WHO and the World Bank, in 2005.

In the earlier study, only a few manufacturers were found to have both the capacity and the interest to supply the so-called “GAVI market” – the group of low-income countries that is reliant on external assistance to introduce new vaccines. There are now more suppliers positioned to provide to that market. Some of these are already providing newer and/or more complex vaccines such as rotavirus, measles-mumps-rubella, meningitis A conjugate, and rabies vaccines to some markets, and others have strong pipelines.

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Are you familiar with efforts to integrate child immunization and family planning services? If so, we need your help.

Family Health International (FHI), through its PROGRESS project, and the Maternal and Child Health Integrated Program (MCHIP), led by Jhpiego with multiple partners, including JSI (which has a long history of working on immunization projects), are collaborating to create an interactive, online map that will indicate countries where family planning messages and/or services have been integrated into child immunization programs.

The online map will include information about where each family planning and child immunization integration project is located, a brief 2 to 4 sentence summary of each project, and a link to an organization, if applicable. We are gathering country-level experiences worldwide. If possible, please take a few moments to send us brief responses to the questions below.

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Faisal Mansoor poses two questions:

  1. If a freeze sensitive vaccine is used after it was frozen, is there any AEFI besides it being less potent?
  2. If there is no adjuvant (in the vaccine), such as Sanofi’s H1N1 liquid 10-dose vaccine, then why are we afraid of freezing?

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by Toryalai Hart

There are, indeed, many glass crushers, some of which are specialized for medical waste glass. ... I do maintain though that if considering use of these devices, it is best to incinerate syringes prior to compaction to neutralize the biohazard and maximally strip the syringes of non-glass components; needle removal would also most likely facilitate compaction in these devices, but testing would need to be systematically undertaken to confirm this approach as feasible and appropriate.

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Photos Courtesy: Mojtaba Haghgou

 

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